BDBM50321199 CHEMBL1163485::rac-3-(4-Nitrophenylamino)-3-cyclohexyl-1-(3-fluorophenyl)-propan-1-one

SMILES [O-][N+](=O)c1ccc(NC(CC(=O)c2cccc(F)c2)C2CCCCC2)cc1

InChI Key InChIKey=IUZRAMZCEBNUIK-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50321199   

TargetProgesterone receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321199(CHEMBL1163485 | rac-3-(4-Nitrophenylamino)-3-cyclo...)
Affinity DataKi:  8.5nMAssay Description:Displacement of [3H]progesterone from human progesterone receptor B after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321199(CHEMBL1163485 | rac-3-(4-Nitrophenylamino)-3-cyclo...)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]DHT from human androgen receptor after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321199(CHEMBL1163485 | rac-3-(4-Nitrophenylamino)-3-cyclo...)
Affinity DataIC50:  193nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321199(CHEMBL1163485 | rac-3-(4-Nitrophenylamino)-3-cyclo...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed