BDBM50321524 CHEMBL1170518::N-(7-acetamido-4-methoxybenzo[d]thiazol-2-yl)-4-fluorobenzamide

SMILES COc1ccc(NC(C)=O)c2sc(NC(=O)c3ccc(F)cc3)nc12

InChI Key InChIKey=BAHHPLVRJISHAN-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50321524   

TargetAdenosine receptor A2b(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321524(CHEMBL1170518 | N-(7-acetamido-4-methoxybenzo[d]th...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor expressed in CHO cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321524(CHEMBL1170518 | N-(7-acetamido-4-methoxybenzo[d]th...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321524(CHEMBL1170518 | N-(7-acetamido-4-methoxybenzo[d]th...)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321524(CHEMBL1170518 | N-(7-acetamido-4-methoxybenzo[d]th...)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321524(CHEMBL1170518 | N-(7-acetamido-4-methoxybenzo[d]th...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321524(CHEMBL1170518 | N-(7-acetamido-4-methoxybenzo[d]th...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321524(CHEMBL1170518 | N-(7-acetamido-4-methoxybenzo[d]th...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human adenosine A2B receptor expressed in CHO cells assessed as decrease in cellular cAMP level after 20 to 25 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321524(CHEMBL1170518 | N-(7-acetamido-4-methoxybenzo[d]th...)
Affinity DataIC50:  350nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of adenosine-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed