BDBM50322346 (R)-Methyl4-(2-(3-((naphthalen-1-ylcarbamoyloxy)methyl)-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-1-yl)acetamido)but-2-enoate::CHEMBL1171636

SMILES COC(=O)\C=C\CNC(=O)CN1c2ccccc2C(=N[C@H](COC(=O)Nc2cccc3ccccc23)C1=O)c1ccccc1

InChI Key InChIKey=UAJOTLYJEAIKDS-SOJHQBKKSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50322346   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
Universit£

Curated by ChEMBL
LigandPNGBDBM50322346((R)-Methyl4-(2-(3-((naphthalen-1-ylcarbamoyloxy)me...)
Affinity DataKi:  930nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
Universit£

Curated by ChEMBL
LigandPNGBDBM50322346((R)-Methyl4-(2-(3-((naphthalen-1-ylcarbamoyloxy)me...)
Affinity DataKi:  3.48E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 after 10 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50322346((R)-Methyl4-(2-(3-((naphthalen-1-ylcarbamoyloxy)me...)
Affinity DataKi:  1.22E+4nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50322346((R)-Methyl4-(2-(3-((naphthalen-1-ylcarbamoyloxy)me...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed