BDBM50322948 (2S,3S)-2-(1-(4-chlorophenyl)-2-(3-fluorophenyl)-3-oxo-2,7-diazaspiro[3.5]nonane-7-carboxamido)-3-methylpentanoic cyanic anhydride::CHEMBL1210983
SMILES CC[C@H](C)[C@H](NC(=O)N1CCC2(CC1)C(N(C2=O)c1cccc(F)c1)c1ccc(Cl)cc1)C(=O)OC#N
InChI Key InChIKey=KGMXXXLUOOBEMV-QPTFRZOZSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50322948
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by whole cell path clamp methodMore data for this Ligand-Target Pair