BDBM50324477 Benzylsulfonyl-D-cyclohexylalanyl-proline-(4-amidinobenzyl)-amide Trifluoroacetate::CHEMBL1215085::CHEMBL1229261
SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC2CCCCC2)NS(=O)(=O)Cc2ccccc2)cc1
InChI Key InChIKey=DJNNZKJZFCRFRX-FTJBHMTQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50324477
Affinity DataKi: 0.102nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.119nMAssay Description:Inhibition of human thrombin using Tos-Gly-Pro-Arg-AMC as substrate after 600 secs by fluorimetric methodMore data for this Ligand-Target Pair
TargetTransmembrane protease serine 11D(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 108nMAssay Description:Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal...More data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Inhibition of human recombinant matriptase 2 expressed in HEK293 cells in conditioned medium after 20 minsMore data for this Ligand-Target Pair
Affinity DataKi: 460nMAssay Description:Inhibition of human purified matriptase 2 catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
University Of Bonn
Curated by ChEMBL
University Of Bonn
Curated by ChEMBL
Affinity DataKi: 770nMAssay Description:Inhibition of human recombinant matriptase catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair