BDBM50326513 (E)-4-Methylamino-but-2-enoicacid[4-(3-chloro-4-fluorophenylamino)-3-cyano-7-(2-fluoroethoxy)-quinolin-6-yl]-amide::CHEMBL1243284

SMILES CNC\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)c(cnc2cc1OCCF)C#N

InChI Key InChIKey=BKVGIHTVFOZUEA-NSCUHMNNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326513   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326513((E)-4-Methylamino-but-2-enoicacid[4-(3-chloro-4-fl...)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326513((E)-4-Methylamino-but-2-enoicacid[4-(3-chloro-4-fl...)
Affinity DataIC50:  8.12nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed