BDBM50326516 (E)-4-{[1-(2-Fluoroethyl)-1H-[1,2,3]triazol-4-ylmethyl]-amino}-but-2-enoic acid[4-(3-chloro-4-fluoro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide::CHEMBL1243283

SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CNCc1cn(CCF)nn1

InChI Key InChIKey=PLNCBERXTZFKGL-ONEGZZNKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326516   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326516((E)-4-{[1-(2-Fluoroethyl)-1H-[1,2,3]triazol-4-ylme...)
Affinity DataIC50:  22.0nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326516((E)-4-{[1-(2-Fluoroethyl)-1H-[1,2,3]triazol-4-ylme...)
Affinity DataIC50:  1.81nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed