BDBM50327047 1-{4-[(5-Methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]-phenyl}-3-phenylurea::CHEMBL1254511::D3RKN_21

SMILES Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4ccccc4)cc3)c12

InChI Key InChIKey=BVFBTDPKGZCIBA-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50327047   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50327047(1-{4-[(5-Methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)ox...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50327047(1-{4-[(5-Methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)ox...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2023More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50327047(1-{4-[(5-Methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)ox...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2022More data for this Ligand-Target Pair
In DepthDetails PubMed