BDBM50327065 1-(3-Methylphenyl)-3-{4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}urea::CHEMBL1254923::D3RKN_19

SMILES Cc1cccc(NC(=O)Nc2ccc(Oc3ncnc4ccn(C)c34)cc2)c1

InChI Key InChIKey=FAICIPSJBXCWEZ-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50327065   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50327065(1-(3-Methylphenyl)-3-{4-[(5-methyl-5H-pyrrolo[3,2-...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50327065(1-(3-Methylphenyl)-3-{4-[(5-methyl-5H-pyrrolo[3,2-...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2023More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50327065(1-(3-Methylphenyl)-3-{4-[(5-methyl-5H-pyrrolo[3,2-...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2022More data for this Ligand-Target Pair
In DepthDetails PubMed