BDBM50327071 1-{3-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)-oxy]phenyl}-3-[3-(trifluoromethyl)phenyl]urea::CHEMBL1254191

SMILES Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cccc(c4)C(F)(F)F)cc3Cl)c12

InChI Key InChIKey=JGJXEXJECKFFGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327071   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50327071(1-{3-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidi...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed