BDBM50327660 11H-Dibenzo[b,e]azepine-1-carboxylic acid methyl ester::CHEMBL1084639::methyl 11H-dibenzo[b,e]azepine-1-carboxylate

SMILES COC(=O)c1cccc2N=Cc3ccccc3Cc12

InChI Key InChIKey=HOEAQVHRGYIZEL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327660   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ferrara University

Curated by ChEMBL
LigandPNGBDBM50327660(11H-Dibenzo[b,e]azepine-1-carboxylic acid methyl e...)
Affinity DataEC50:  0.575nMAssay Description:Activation of human TRPA1 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ferrara University

Curated by ChEMBL
LigandPNGBDBM50327660(11H-Dibenzo[b,e]azepine-1-carboxylic acid methyl e...)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed