BDBM50327661 11H-dibenzo[b,e]azepine-2-carboxylic acid methyl ester::CHEMBL1085103::methyl 11H-dibenzo[b,e]azepine-2-carboxylate

SMILES COC(=O)c1ccc2N=Cc3ccccc3Cc2c1

InChI Key InChIKey=FGCXWJVMYQZREN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327661   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ferrara University

Curated by ChEMBL
LigandPNGBDBM50327661(11H-dibenzo[b,e]azepine-2-carboxylic acid methyl e...)
Affinity DataEC50:  0.575nMAssay Description:Activation of human TRPA1 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ferrara University

Curated by ChEMBL
LigandPNGBDBM50327661(11H-dibenzo[b,e]azepine-2-carboxylic acid methyl e...)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed