BDBM50327676 CHEMBL1084097::Dibenzo[b,f][1,4]oxazepine-6-carboxylic acid amide::dibenzo[b,f][1,4]oxazepine-6-carboxamide

SMILES NC(=O)c1cccc2N=Cc3ccccc3Oc12

InChI Key InChIKey=PTHBOTMILXORGK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327676   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ferrara University

Curated by ChEMBL
LigandPNGBDBM50327676(CHEMBL1084097 | Dibenzo[b,f][1,4]oxazepine-6-carbo...)
Affinity DataEC50:  0.115nMAssay Description:Activation of human TRPA1 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ferrara University

Curated by ChEMBL
LigandPNGBDBM50327676(CHEMBL1084097 | Dibenzo[b,f][1,4]oxazepine-6-carbo...)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed