BDBM50328080 3-(6-(1H-indazol-4-yl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-2,2-dimethylpropan-1-ol::CHEMBL1257419

SMILES Cn1ncc2c(NCC(C)(C)CO)nc(nc12)-c1cccc2[nH]ncc12

InChI Key InChIKey=ROHHOJPPPCTPKV-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328080   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50328080(3-(6-(1H-indazol-4-yl)-1-methyl-1H-pyrazolo[3,4-d]...)Copy SMILESCopy InChI

Affinity DataIC50:  1.10nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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