BDBM50328082 6-(1H-indazol-4-yl)-1-methyl-N-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL1257534

SMILES Cn1ncc2c(Nc3ccc(cc3)S(C)(=O)=O)nc(nc12)-c1cccc2[nH]ncc12

InChI Key InChIKey=UMAGBLRZYBDBEW-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328082   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50328082(6-(1H-indazol-4-yl)-1-methyl-N-(4-(methylsulfonyl)...)Copy SMILESCopy InChI

Affinity DataIC50:  1.40nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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