BDBM50328326 1-(3-ethylphenoxy)-3-(1-(5-phenylthieno[2,3-d]pyrimidin-4-yl)piperidin-4-ylamino)propan-2-ol::CHEMBL1258484

SMILES CCc1cccc(OCC(O)CNC2CCN(CC2)c2ncnc3scc(-c4ccccc4)c23)c1

InChI Key InChIKey=CBIPUOCUMCGWSC-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50328326   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328326(1-(3-ethylphenoxy)-3-(1-(5-phenylthieno[2,3-d]pyri...)
Affinity DataKi:  10nMAssay Description:Displacement of [125I]-cyanopindolol from human adrenergic beta2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328326(1-(3-ethylphenoxy)-3-(1-(5-phenylthieno[2,3-d]pyri...)
Affinity DataKi:  63nMAssay Description:Displacement of [125I]-cyanopindolol from human adrenergic beta3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328326(1-(3-ethylphenoxy)-3-(1-(5-phenylthieno[2,3-d]pyri...)
Affinity DataKi:  289nMAssay Description:Agonist activity at human recombinant adrenergic beta-1 receptor expressed in CHO cells assessed as cyclic AMP formation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328326(1-(3-ethylphenoxy)-3-(1-(5-phenylthieno[2,3-d]pyri...)
Affinity DataEC50:  264nMAssay Description:Agonist activity at human recombinant adrenergic beta3 receptor expressed in CHO cells assessed as cyclic AMP formation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed