BDBM50329517 (R)-2-amino-4-(4-(difluoromethoxy)phenyl)-4-(3-(2-fluoropyridin-3-yl)phenyl)-1-methyl-1H-imidazol-5(4H)-one::CHEMBL1271244
SMILES CN1C(N)=N[C@](C1=O)(c1ccc(OC(F)F)cc1)c1cccc(c1)-c1cccnc1F
InChI Key InChIKey=OMAQNCHXLTWMDV-JOCHJYFZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50329517
Affinity DataEC50: 27nMAssay Description:Inhibition of human recombinant BACE1 expressed in CHO cells assessed as reduction in amyloid beta level by sandwich ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of cathepsin D by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair