BDBM50329763 4-[N-(6-Chloro-5-formyl-2-methylthiopyrimidin-4-yl)amino]benzenesulfonamide::4-{[6-chloro-5-formyl-2-(methylsulfanyl)pyrimidin-4-yl]amino}benzenesulfonamide::CHEMBL1233721

SMILES CSc1nc(Cl)c(C=O)c(Nc2ccc(cc2)S(N)(=O)=O)n1

InChI Key InChIKey=KJYFMIWARJDIAU-UHFFFAOYSA-N

Data  5 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50329763   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329763(4-[N-(6-Chloro-5-formyl-2-methylthiopyrimidin-4-yl...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 1 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329763(4-[N-(6-Chloro-5-formyl-2-methylthiopyrimidin-4-yl...)
Affinity DataKd:  2.80E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 1 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329763(4-[N-(6-Chloro-5-formyl-2-methylthiopyrimidin-4-yl...)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 7 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329763(4-[N-(6-Chloro-5-formyl-2-methylthiopyrimidin-4-yl...)
Affinity DataKd:  320nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 2 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50329763(4-[N-(6-Chloro-5-formyl-2-methylthiopyrimidin-4-yl...)
Affinity DataKd:  170nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 2 by thermal shift assayMore data for this Ligand-Target Pair