BDBM50330253 5,5'-Bis(2-cyclohexylethyl)-6,6',7,7'-tetrahydroxy-3,3'-dimethyl-2,2'-binaphthyl-1,1',4,4'-tetraone::CHEMBL1269074

SMILES Oc1cc2c(O)c(-c3c(O)c4cc(O)c(O)c(=CCC5CCCCC5)c4c(O)c3=C)c(=C)c(O)c2c(=CCC2CCCCC2)c1O

InChI Key InChIKey=CKZWQJXQGQJMSG-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50330253   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50330253(5,5'-Bis(2-cyclohexylethyl)-6,6',7,7'-tetrahydroxy...)
Affinity DataKi:  3.93E+3nMAssay Description:Displacement of F-BakBH3 from Mcl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50330253(5,5'-Bis(2-cyclohexylethyl)-6,6',7,7'-tetrahydroxy...)
Affinity DataKi:  4.47E+3nMAssay Description:Displacement of F-BakBH3 from Bcl-2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50330253(5,5'-Bis(2-cyclohexylethyl)-6,6',7,7'-tetrahydroxy...)
Affinity DataKi:  8.40E+3nMAssay Description:Displacement of F-BakBH3 from Bcl-xL after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50330253(5,5'-Bis(2-cyclohexylethyl)-6,6',7,7'-tetrahydroxy...)
Affinity DataIC50:  5.90E+3nMAssay Description:Displacement of F-BakBH3 from Mcl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50330253(5,5'-Bis(2-cyclohexylethyl)-6,6',7,7'-tetrahydroxy...)
Affinity DataIC50:  1.27E+4nMAssay Description:Displacement of F-BakBH3 from Bcl-xL after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50330253(5,5'-Bis(2-cyclohexylethyl)-6,6',7,7'-tetrahydroxy...)
Affinity DataIC50:  6.73E+3nMAssay Description:Displacement of F-BakBH3 from Bcl-2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed