BDBM50330254 6,6',7,7'-Tetrahydroxy-3,3'-dimethyl-5,5'-diphenethyl-2,2'-binaphthyl-1,1',4,4'-tetraone::CHEMBL1269075

SMILES Oc1cc2c(O)c(-c3c(O)c4cc(O)c(O)c(=CCc5ccccc5)c4c(O)c3=C)c(=C)c(O)c2c(=CCc2ccccc2)c1O

InChI Key InChIKey=FDAUMAPDGONGQR-UHFFFAOYSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50330254   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50330254(6,6',7,7'-Tetrahydroxy-3,3'-dimethyl-5,5'-diphenet...)
Affinity DataKi:  870nMAssay Description:Displacement of F-BakBH3 from Mcl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50330254(6,6',7,7'-Tetrahydroxy-3,3'-dimethyl-5,5'-diphenet...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of F-BakBH3 from Bcl-xL after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50330254(6,6',7,7'-Tetrahydroxy-3,3'-dimethyl-5,5'-diphenet...)
Affinity DataKi:  1.73E+3nMAssay Description:Displacement of F-BakBH3 from Bcl-2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50330254(6,6',7,7'-Tetrahydroxy-3,3'-dimethyl-5,5'-diphenet...)
Affinity DataKi:  6.47E+3nMAssay Description:Displacement of F-BakBH3 from Bfl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50330254(6,6',7,7'-Tetrahydroxy-3,3'-dimethyl-5,5'-diphenet...)
Affinity DataIC50:  1.29E+3nMAssay Description:Displacement of F-BakBH3 from Mcl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50330254(6,6',7,7'-Tetrahydroxy-3,3'-dimethyl-5,5'-diphenet...)
Affinity DataIC50:  1.79E+3nMAssay Description:Displacement of F-BakBH3 from Bcl-xL after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50330254(6,6',7,7'-Tetrahydroxy-3,3'-dimethyl-5,5'-diphenet...)
Affinity DataIC50:  2.57E+3nMAssay Description:Displacement of F-BakBH3 from Bcl-2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50330254(6,6',7,7'-Tetrahydroxy-3,3'-dimethyl-5,5'-diphenet...)
Affinity DataIC50:  9.72E+3nMAssay Description:Displacement of F-BakBH3 from Bfl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed