BDBM50331978 5-((2-(4-(2,4-dichlorophenyl)piperazin-1-yl)-2-oxoethoxy)methyl)thiophene-2-carbonitrile::CHEMBL1290444
SMILES Clc1ccc(N2CCN(CC2)C(=O)COCc2ccc(s2)C#N)c(Cl)c1
InChI Key InChIKey=NMWCHQPXBFRMQA-UHFFFAOYSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50331978
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 210nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair