BDBM50332301 (5-amino-3-(phenylamino)-1H-1,2,4-triazol-1-yl)(2,6-difluorophenyl)methanone::CHEMBL1287971

SMILES Nc1nc(Nc2ccccc2)nn1C(=O)c1c(F)cccc1F

InChI Key InChIKey=VWXZXMUTJDFDBX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50332301   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50332301((5-amino-3-(phenylamino)-1H-1,2,4-triazol-1-yl)(2,...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human recombinant JAK1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50332301((5-amino-3-(phenylamino)-1H-1,2,4-triazol-1-yl)(2,...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human recombinant TYK2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50332301((5-amino-3-(phenylamino)-1H-1,2,4-triazol-1-yl)(2,...)
Affinity DataIC50:  3.25E+3nMAssay Description:Inhibition of human recombinant JAK3 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed