BDBM50333542 5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfonyl)-2,3-dihydro-1H-quinolin-4-one::CHEMBL1642117

SMILES CN1CCN(CC1)c1cccc2N(CCC(=O)c12)S(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=TZMHJAWORUSIEG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50333542   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50:  61nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50:  333nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50:  760nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50:  1.79E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D4 receptor expressed in cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50:  620nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptor expressed in cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50:  2.92E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50:  438nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed in cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed