BDBM50333553 2,7-dimethyl-5-(4-methylpiperazin-1-yl)-1-(naphthalen-2-ylsulfonyl)-2,3-dihydroquinolin-4(1H)-one::CHEMBL1642128

SMILES CC1CC(=O)c2c(cc(C)cc2N1S(=O)(=O)c1ccc2ccccc2c1)N1CCN(C)CC1

InChI Key InChIKey=NFWRARMIHODAKJ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50333553   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333553(2,7-dimethyl-5-(4-methylpiperazin-1-yl)-1-(naphtha...)
Affinity DataIC50:  11nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333553(2,7-dimethyl-5-(4-methylpiperazin-1-yl)-1-(naphtha...)
Affinity DataIC50:  1.23E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333553(2,7-dimethyl-5-(4-methylpiperazin-1-yl)-1-(naphtha...)
Affinity DataIC50:  704nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333553(2,7-dimethyl-5-(4-methylpiperazin-1-yl)-1-(naphtha...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D4 receptor expressed in cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333553(2,7-dimethyl-5-(4-methylpiperazin-1-yl)-1-(naphtha...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptor expressed in cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333553(2,7-dimethyl-5-(4-methylpiperazin-1-yl)-1-(naphtha...)
Affinity DataIC50:  1.78E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333553(2,7-dimethyl-5-(4-methylpiperazin-1-yl)-1-(naphtha...)
Affinity DataIC50:  180nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333553(2,7-dimethyl-5-(4-methylpiperazin-1-yl)-1-(naphtha...)
Affinity DataIC50:  19nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed in cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed