BDBM50333655 4-oxo-N-p-tolyl-4H-chromene-3-carboxamide::CHEMBL1643124

SMILES Cc1ccc(NC(=O)c2coc3ccccc3c2=O)cc1

InChI Key InChIKey=ZPHGXJAOXHSRAX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333655   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50333655(4-oxo-N-p-tolyl-4H-chromene-3-carboxamide | CHEMBL...)
Affinity DataIC50:  68nMAssay Description:Inhibition of human recombinant MAOB expressed in baculovirus-infected BTI insect cells after 15 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50333655(4-oxo-N-p-tolyl-4H-chromene-3-carboxamide | CHEMBL...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human microsomal MAO-B expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50333655(4-oxo-N-p-tolyl-4H-chromene-3-carboxamide | CHEMBL...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human microsomal MAO-B expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed