BDBM50333917 (S)-2-(5,7-dichloro-2-(pyrazolo[1,5-a]pyridine-2-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(1-isopropyl-1H-1,2,3-triazol-4-yl)propanoic acid::CHEMBL1644131

SMILES CC(C)n1cc(C[C@H](NC(=O)c2c(Cl)cc3CN(CCc3c2Cl)C(=O)c2cc3ccccn3n2)C(O)=O)nn1

InChI Key InChIKey=UYUMTQVAGHXLJZ-NRFANRHFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333917   

TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333917((S)-2-(5,7-dichloro-2-(pyrazolo[1,5-a]pyridine-2-c...)
Affinity DataIC50:  7nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333917((S)-2-(5,7-dichloro-2-(pyrazolo[1,5-a]pyridine-2-c...)
Affinity DataIC50:  260nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed