BDBM50333976 CHEMBL1644609::exo-2-(6-((1R,5S)-8-azabicyclo[3.2.1]octan-3-yloxy)pyridin-2-yl)benzonitrile

SMILES N#Cc1ccccc1-c1cccc(O[C@H]2C[C@@H]3CC[C@H](C2)N3)n1

InChI Key InChIKey=SCEZKNSHVTVFNV-MUJYYYPQSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333976   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333976(CHEMBL1644609 | exo-2-(6-((1R,5S)-8-azabicyclo[3.2...)
Affinity DataKi:  7.08E+3nMAssay Description:Inhibition of human ERG by dofetilide binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333976(CHEMBL1644609 | exo-2-(6-((1R,5S)-8-azabicyclo[3.2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333976(CHEMBL1644609 | exo-2-(6-((1R,5S)-8-azabicyclo[3.2...)
Affinity DataIC50:  9nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333976(CHEMBL1644609 | exo-2-(6-((1R,5S)-8-azabicyclo[3.2...)
Affinity DataIC50:  8.98E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed