BDBM50334187 3,4-Difluoro-N-(pyridin-3-yl)benzamide::CHEMBL1645416

SMILES Fc1ccc(cc1F)C(=O)Nc1cccnc1

InChI Key InChIKey=GEALXINOAKIWDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334187   

TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334187(3,4-Difluoro-N-(pyridin-3-yl)benzamide | CHEMBL164...)
Affinity DataIC50:  53.5nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334187(3,4-Difluoro-N-(pyridin-3-yl)benzamide | CHEMBL164...)
Affinity DataIC50:  5.92E+3nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed