BDBM50334191 4-Chloro-N-(pyridin-3-yl)benzamide::CHEMBL1645408

SMILES Clc1ccc(cc1)C(=O)Nc1cccnc1

InChI Key InChIKey=BGSUATYDORXBCT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50334191   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334191(4-Chloro-N-(pyridin-3-yl)benzamide | CHEMBL1645408)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50334191(4-Chloro-N-(pyridin-3-yl)benzamide | CHEMBL1645408)
Affinity DataIC50:  420nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334191(4-Chloro-N-(pyridin-3-yl)benzamide | CHEMBL1645408)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human CYP11B1 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycortisol as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50334191(4-Chloro-N-(pyridin-3-yl)benzamide | CHEMBL1645408)
Affinity DataIC50:  65nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed