BDBM50334191 4-Chloro-N-(pyridin-3-yl)benzamide::CHEMBL1645408
SMILES Clc1ccc(cc1)C(=O)Nc1cccnc1
InChI Key InChIKey=BGSUATYDORXBCT-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50334191
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland
Curated by ChEMBL
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland
Curated by ChEMBL
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland
Curated by ChEMBL
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human CYP11B1 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycortisol as substrate by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair