BDBM50334767 (2R,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-2-amine::CHEMBL1642897::cis-(2R,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-2-amine
SMILES CN[C@@H]1C[C@H](c2ccc(Cl)c(Cl)c2)c2ccccc2C1
InChI Key InChIKey=KDERKEZKMQCRPQ-DZGCQCFKSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50334767
Affinity DataIC50: 107nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sepracor
Curated by ChEMBL
Sepracor
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 107nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair