BDBM50334781 CHEMBL1642912::Cis-2-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-2-yl)ethanamine
SMILES NCC[C@H]1C[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc2C1
InChI Key InChIKey=SNDGNPRZZZPUAX-WBMJQRKESA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50334781
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sepracor
Curated by ChEMBL
Sepracor
Curated by ChEMBL
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair