BDBM50337823 1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)pyrrolidine::CHEMBL1683877::US10562878, Compound 111

SMILES Clc1ccc(cc1Cl)C1(CN2CCCC2)CCCCC1

InChI Key InChIKey=YWOVEHIRDVATGZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50337823   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337823(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)pyrrol...)
Affinity DataIC50:  8.57E+3nMAssay Description:Inhibition of human recombinant serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337823(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)pyrrol...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337823(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)pyrrol...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337823(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)pyrrol...)
Affinity DataIC50:  8.57E+3nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337823(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)pyrrol...)
Affinity DataIC50:  232nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337823(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)pyrrol...)
Affinity DataIC50:  232nMAssay Description:Inhibition of human recombinant Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed