BDBM50338313 (+/-)-3-((3R,4S)-3-hydroxy-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinolin-5-yl)acrylonitrile::CHEMBL1682428

SMILES C[C@@H]1[C@@H](O)C(C)(C)Nc2c(C)cc(c(\C=C\C#N)c12)-c1cccc2cc[nH]c12

InChI Key InChIKey=FEMGRFJEGDQZBL-XQTZDJHXSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338313   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338313((+/-)-3-((3R,4S)-3-hydroxy-6-(1H-indol-7-yl)-2,2,4...)
Affinity DataEC50:  5.70nMAssay Description:Agonist activity at GR expressed in african green monkey CV1 cells transfected with luciferase gene linked to MMTV promoter assessed as induction of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed