BDBM50340004 (R)-2-(3-amino-1-(isoxazol-5-yl)propoxy)-6-(trifluoromethyl)nicotinonitrile oxalate::CHEMBL1762481
SMILES NCC[C@@H](Oc1nc(ccc1C#N)C(F)(F)F)c1ccno1
InChI Key InChIKey=SDRHZGGFUFCFFW-SECBINFHSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50340004
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Astrazeneca Charnwood
Curated by ChEMBL
Astrazeneca Charnwood
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Astrazeneca Charnwood
Curated by ChEMBL
Astrazeneca Charnwood
Curated by ChEMBL
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of serotonin transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca Charnwood
Curated by ChEMBL
Astrazeneca Charnwood
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Inhibition of iNOS in intact human DLD1 cells assessed as nitric oxide productionMore data for this Ligand-Target Pair
Affinity DataIC50: >1.40E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair