BDBM50340599 7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morpholino-1H-1,2,4-triazol-1-yl)phenyl)quinazolin-2-amine::CHEMBL1761554

SMILES Cn1cc(cn1)-c1ccc2cnc(Nc3ccc(cc3)-n3cnc(n3)N3CCOCC3)nc2c1

InChI Key InChIKey=HGQHCYUSXPTRID-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50340599   

TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50340599(7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morpholino-1H...)
Affinity DataIC50:  310nMAssay Description:Inhibition of JNK3-mediated c-jun phosphorylation in rat INS1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50340599(7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morpholino-1H...)
Affinity DataIC50:  50nMAssay Description:Inhibition of JNK1 (unknown origin) by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50340599(7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morpholino-1H...)
Affinity DataIC50:  310nMAssay Description:Inhibition of c-JunMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50340599(7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morpholino-1H...)
Affinity DataIC50:  90nMAssay Description:Inhibition of JNK3 by HRTFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50340599(7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morpholino-1H...)
Affinity DataIC50:  50nMAssay Description:Inhibition of JNK1 by HRTFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50340599(7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morpholino-1H...)
Affinity DataIC50:  90nMAssay Description:Inhibition of JNK2 (unknown origin) by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed