BDBM50343769 (S)-1-(4-(7,7-Dimethyl-4-(3-methylmorpholino)-5,7-dihydrofuro[3,4-d]pyrimidin-2-yl)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)urea::CHEMBL1774358
SMILES C[C@H]1COCCN1c1nc(nc2c1COC2(C)C)-c1ccc(NC(=O)Nc2cnn(C)c2)cc1
InChI Key InChIKey=NIVQDDVZJRCEDJ-HNNXBMFYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50343769
Affinity DataKi: 0.800nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells using 4E-BP1 substrate after 30 mins by fluorescence resonance energy transfer assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of mTOR in human NCI-PC3 cells assessed as inhibition of p70S6k phosphorylation by electrochemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of mTor in human NCI-PC3 cells assessed as inhibition of Akt phosphorylation at serine473 by electrochemiluminescence assayMore data for this Ligand-Target Pair