BDBM50344016 2-((5-methyl-2-phenyloxazol-4-yl)methyl)-N-((6-methylpyridin-2-yl)methyl)-1,2,3,4-tetrahydroisoquinoline-4-carboxamide::CHEMBL1779976

SMILES Cc1oc(nc1CN1CC(C(=O)NCc2cccc(C)n2)c2ccccc2C1)-c1ccccc1

InChI Key InChIKey=KTZOPPLFULGANJ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344016   

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50344016(2-((5-methyl-2-phenyloxazol-4-yl)methyl)-N-((6-met...)Copy SMILESCopy InChI

Affinity DataIC50:  5nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50344016(2-((5-methyl-2-phenyloxazol-4-yl)methyl)-N-((6-met...)Copy SMILESCopy InChI

Affinity DataIC50:  1.80nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI