BDBM50344018 CHEMBL1779984::trans-(3R,5R)-5-ethyl-1-((5-methyl-2-phenyloxazol-4-yl)methyl)-N-((6-methylpyridin-2-yl)methyl)piperidine-3-carboxamide

SMILES CC[C@@H]1C[C@H](CN(Cc2nc(oc2C)-c2ccccc2)C1)C(=O)NCc1cccc(C)n1

InChI Key InChIKey=DWHZRFMVWCPXSM-IFMALSPDSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344018   

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50344018(CHEMBL1779984 | trans-(3R,5R)-5-ethyl-1-((5-methyl...)Copy SMILESCopy InChI

Affinity DataIC50:  6nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50344018(CHEMBL1779984 | trans-(3R,5R)-5-ethyl-1-((5-methyl...)Copy SMILESCopy InChI

Affinity DataIC50:  1.80nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI