BDBM50344285 CHEMBL1779047::quinuclidin-4-yl biphenyl-2-ylcarbamate hydrochloride

SMILES O=C(Nc1ccccc1-c1ccccc1)OC12CCN(CC1)CC2

InChI Key InChIKey=XHIQZUNDUKHSQA-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50344285   

TargetMuscarinic acetylcholine receptor M3(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50344285(CHEMBL1779047 | quinuclidin-4-yl biphenyl-2-ylcarb...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M3 receptor in submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50344285(CHEMBL1779047 | quinuclidin-4-yl biphenyl-2-ylcarb...)
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M1 receptor in cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50344285(CHEMBL1779047 | quinuclidin-4-yl biphenyl-2-ylcarb...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M2 receptor in heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50344285(CHEMBL1779047 | quinuclidin-4-yl biphenyl-2-ylcarb...)
Affinity DataIC50:  14.5nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50344285(CHEMBL1779047 | quinuclidin-4-yl biphenyl-2-ylcarb...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50344285(CHEMBL1779047 | quinuclidin-4-yl biphenyl-2-ylcarb...)
Affinity DataIC50:  6nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed