BDBM50344506 5-chloro-2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo[3.2.1]octan-3-yloxy)-5-methylpyrimidin-4-yloxy)benzonitrile::CHEMBL1778243

SMILES Cc1c(OC2C[C@@H]3CC[C@@H](C2)N3S(=O)(=O)C2CC2)ncnc1Oc1ccc(Cl)cc1C#N

InChI Key InChIKey=WSMCJUQLYRJJBO-IRXDYDNUSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344506   

TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344506(5-chloro-2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-a...)
Affinity DataEC50:  290nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344506(5-chloro-2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-a...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed