BDBM50344591 (E)-N-(4-(3-(5-bromo-4-hydroxy-2-methoxyphenyl)acryloyl)phenyl)-4-tert-butylbenzamide::CHEMBL1778928

SMILES COc1cc(O)c(Br)cc1\C=C\C(=O)c1ccc(NC(=O)c2ccc(cc2)C(C)(C)C)cc1

InChI Key InChIKey=DXMJLJVICPDLPI-NTEUORMPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344591   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50344591((E)-N-(4-(3-(5-bromo-4-hydroxy-2-methoxyphenyl)acr...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of recombinant human PTP1B using p-nitrophenyl phosphate as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed