BDBM50344622 CHEMBL1779057::licochalcone E

SMILES COc1cc(O)c(cc1\C=C\C(=O)c1ccc(O)cc1)[C@@H](C)C(C)=C

InChI Key InChIKey=SWPKMTGYQGHLJS-RNVIBTMRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344622   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50344622(CHEMBL1779057 | licochalcone E)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50344622(CHEMBL1779057 | licochalcone E)
Affinity DataIC50:  2.07E+4nMAssay Description:Inhibition of recombinant human PTP1B using p-nitrophenyl phosphate as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed