BDBM50344902 1,2-dibenzyl-5-ethyl-2',3',5,8-tetrahydrospiro[imidazo[2,1-b]purine-7,1'-inden]-4(1H)-one::CHEMBL1778033
SMILES CCN1C2=NC3(CCc4ccccc34)CN2c2c(nc(Cc3ccccc3)n2Cc2ccccc2)C1=O
InChI Key InChIKey=YAQRTUXYVQSHDL-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50344902
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human ERG by voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
Affinity DataIC50: 233nMAssay Description:Antagonist activity at rat P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 248nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair