BDBM50344994 2-(5-chloro-3'-cyanobiphenyl-2-yloxy)acetic acid::CHEMBL1778636

SMILES OC(=O)COc1ccc(Cl)cc1-c1cccc(c1)C#N

InChI Key InChIKey=LKVOYKPVSRJIAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344994   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344994(2-(5-chloro-3'-cyanobiphenyl-2-yloxy)acetic acid |...)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344994(2-(5-chloro-3'-cyanobiphenyl-2-yloxy)acetic acid |...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human CRTh2 receptor expressed in CHO cells assessed as inhibition of PGD2-induced calcium flux in presence of 1% bovine serum...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed