BDBM50345754 3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylpiperazin-1-yl-methyl)-1H-indole::CHEMBL1785074

SMILES CN1CCN(Cc2ccc3n(cc(Cl)c3c2)S(=O)(=O)c2ccc(F)cc2)CC1

InChI Key InChIKey=DLIQQIYDZNPGLQ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50345754   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345754(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylp...)
Affinity DataKi:  2.97nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345754(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylp...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 5HT7 receptor expressed in CHO cells after 5 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345754(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylp...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 5HT4 receptor expressed in CHO cells after 5 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345754(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylp...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human muscarinic M1 receptor expressed in CHO cells after 5 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed