BDBM50346375 4-[3-[4-(naphthalen)piperazin-1-yl]propoxy]-4-aza-tricyclo [5.2.1.02,6]dec-8-ene-3,5-dione::CHEMBL1783351

SMILES O=C1C2C3CC(C=C3)C2C(=O)N1OCCCN1CCN(CC1)c1cccc2ccccc12

InChI Key InChIKey=RUFAUUMYKFPZQN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50346375   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346375(4-[3-[4-(naphthalen)piperazin-1-yl]propoxy]-4-aza-...)
Affinity DataKi:  0.293nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346375(4-[3-[4-(naphthalen)piperazin-1-yl]propoxy]-4-aza-...)
Affinity DataKi:  91.8nMAssay Description:Displacement of [3H]Ketanserin from 5HT2A receptor in Sprague-Dawley rat frontal cortical homogenates after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346375(4-[3-[4-(naphthalen)piperazin-1-yl]propoxy]-4-aza-...)
Affinity DataKi:  263nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Universit£

Curated by ChEMBL
LigandPNGBDBM50346375(4-[3-[4-(naphthalen)piperazin-1-yl]propoxy]-4-aza-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed