BDBM50351409 CHEMBL1819200

SMILES O[C@H]1[C@H](O)[C@H]2COCCCCOc3cc(Cl)c(Cc4ccc5OCCOc5c4)cc3[C@H](O2)[C@@H]1O

InChI Key InChIKey=NWXNQOPEBMMIML-RXFVIIJJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50351409   

TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351409(CHEMBL1819200)
Affinity DataIC50:  3.65nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351409(CHEMBL1819200)
Affinity DataIC50:  3.65nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent