BDBM50351482 CHEMBL1819612

SMILES CN1C[C@@H](COc2ccc(C(=O)Nc3cc(C)cc(CC(O)=O)c3)c(C)c2)Oc2ccccc12

InChI Key InChIKey=LYNRZWODOXOKCD-QFIPXVFZSA-N

Data  8 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50351482   

TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351482(CHEMBL1819612)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]PGD2 from mouse prostanoid DP receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351482(CHEMBL1819612)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]PGE2 from mouse prostaglandin EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351482(CHEMBL1819612)
Affinity DataKi:  670nMAssay Description:Displacement of [3H]PGE2 from mouse prostaglandin EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351482(CHEMBL1819612)
Affinity DataKi:  3.50E+3nMAssay Description:Displacement of [3H]Iloprost from human prostanoid IP receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351482(CHEMBL1819612)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-SQ29548 from human prostanoid TP receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351482(CHEMBL1819612)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse prostaglandin EP3alpha receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351482(CHEMBL1819612)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse prostaglandin EP1 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(MOUSE)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351482(CHEMBL1819612)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGF2alpha from mouse prostanoid FP receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351482(CHEMBL1819612)
Affinity DataIC50:  3.40nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed