BDBM50351484 CHEMBL1819623

SMILES CN1C[C@@H](COc2ccc(C(=O)Nc3cc(CC(O)=O)ccc3F)c(Cl)c2)Oc2ccccc12

InChI Key InChIKey=NYJIUFYVDCEUIV-KRWDZBQOSA-N

Data  10 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50351484   

TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351484(CHEMBL1819623)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351484(CHEMBL1819623)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]PGD2 from mouse prostanoid DP receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351484(CHEMBL1819623)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]PGE2 from mouse prostaglandin EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(MOUSE)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351484(CHEMBL1819623)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGF2alpha from mouse prostanoid FP receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351484(CHEMBL1819623)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Iloprost from human prostanoid IP receptor expressed in CHO cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351484(CHEMBL1819623)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Iloprost from human prostanoid IP receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351484(CHEMBL1819623)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse prostaglandin EP3alpha receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351484(CHEMBL1819623)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse prostaglandin EP1 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351484(CHEMBL1819623)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse prostaglandin EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351484(CHEMBL1819623)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-SQ29548 from human prostanoid TP receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351484(CHEMBL1819623)
Affinity DataIC50:  7.40nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP production after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351484(CHEMBL1819623)
Affinity DataIC50:  7.40nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed