BDBM50352044 CHEMBL1824007

SMILES FC(F)(F)c1ccc(nc1)-c1ccc(Cl)c(c1)C(=O)NCCc1ccccc1Cl

InChI Key InChIKey=OBKVOVQRLZZJGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50352044   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50352044(CHEMBL1824007)
Affinity DataIC50:  4.60E+3nMAssay Description:Antagonist activity at P2X7R expressed in LPS-activated human monocytes assessed as inhibition of ATP-induced IL-1beta release in presence of low ser...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed